TY  - BOOK
AU  - Mrozek,Dariusz
ED  - SpringerLink (Online service)
TI  - High-Performance Computational Solutions in Protein Bioinformatics
T2  - SpringerBriefs in Computer Science,
SN  - 9783319069715
AV  - QH324.2-324.25 
U1  - 570.285 23
PY  - 2014///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Computer science
KW  - Computer Communication Networks
KW  - Bioinformatics
KW  - Biochemistry
KW  - Computer Science
KW  - Computational Biology/Bioinformatics
KW  - Protein Structure
KW  - Processor Architectures
KW  - Mathematical and Computational Biology
N1  - Formal Model of 3D Protein Structures for Functional Genomics, Comparative Bioinformatics, and Molecular Modeling -- Multithreaded PSS-SQL for Searching Databases of Secondary Structures -- GPU and CUDA for 3D Protein Structure Similarity Searching -- Cloud Computing for 3D Protein Structure Alignment -- General Discussion and Concluding Remarks
N2  - Recent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation levels, and various techniques that can be used to accelerate similarity searches. Divided into four parts, the first part provides a formal model of 3D protein structures for functional genomics, comparative bioinformatics, and molecular modeling. The second part focuses on the use of multithreading for efficient approximate searching on protein secondary structures. The third and fourth parts concentrate on finding 3D protein structure similarities with the support of GPUs and cloud computing. Parts three and four both describe the acceleration of different methods. The text will be of interest to researchers and software developers working in the field of structural bioinformatics and biomedical databases
UR  - http://dx.doi.org/10.1007/978-3-319-06971-5
ER  -