New Antibody Microarray Tube for Cellular Localization and Signaling Pathways [electronic resource] / by Lin Wang, Minghu Jiang, Stefan Wölfl.

Technologies -- New Cytoplasmic and Nuclear BMP2-Signaling Pattern in U937 Cells -- New Cytoplasmic and Nuclear BMP2-Signaling in MCF7 Cells -- New Cytoplasmic and Nuclear STI571 Signaling in K562 Cells -- Positive and Negative Co-localized Relationships in Three Treated Cell Lines -- Cytoplasmic Signaling in Three Treated Cell Lines -- Proteomic Silencing in Treated Human Cancer Cell Lines -- Signaling Pathway Setting-up Based on Bioinformatics.

New Antibody Microarray Tube for Cellular Localization and Signaling Pathways describes a new integrated protein biochip system including protein localization, biocomputing and signaling pathways. In the post-genome era, proteomics study for direct analysis of a group of proteins becomes more and more important. Identification of its location often provides crucial information for understanding the function or regulation of a given protein in biological pathways. The book discusses a new microarray tube with incorporation of nuclear and cytoplasmic protein purification and biocomputing technologies, intended for setting-up signaling pathways and making new discoveries. The book is intended for researchers in the fields of medicine, biology, electronics, pharmacy, computer science and mathematics. Lin Wang is an associate professor at the Biomedical Engineering Center, Beijing University of Posts and Telecommunications, China.